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发布日期:2023-02-23
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梁箫 副教授


梁箫,女,满族,19832月生,辽宁大连人博士,副教授、硕士生导师。水生生物系专任教师。兼任中国海洋湖沼学会养殖生态学分会副秘书长、国家现代海洋牧场科技创新联盟专家委员会委员,学术期刊Frontiers in Marine Science客座主编。

 

教育背景

20123月毕业于日本长崎大学生产科学研究科海洋生产科学专业,获博士学位。

20093月毕业于日本长崎大学生产科学研究科水产学专业,获硕士学位

2006年毕业于大连海洋大学水产养殖专业,获学士学位

 

教学工作情况

本科生课程:贝类学、贝类增养殖学、蛋白质组学、微生物生态学;

研究生课程:污损生物学、贝类人工繁育、酶与蛋白质、高级水生生物学(博士)。

 

主要研究方向

海洋细菌胞外蛋白在贻贝发育中的作用研究;

受体调控贻贝附着的分子机制研究;

环境变化对贝类生长发育分子机制研究;

海洋生物活性物质的开发与应用研究。

 

主持和参与的科教项目

[1] 国家重点研发计划“战略性科技创新合作”重点专项项目,中国-葡萄牙星海“一带一路”联合实验室建设与联合研究2022.11-2025.10,承担任务

[2] 上海市科委高端外国专家项目,厚壳贻贝对海洋生物被膜附着响应的机制研究2022.01-2022.12,主持

[3] 国家自然科学基金青年项目厚壳贻贝肾上腺素能受体和5-羟色胺受体调控幼虫变态的分子机理研究,2017.01-2019.12,主持

[4] 上海市青年优秀学术带头人计划厚壳贻贝幼虫附着变态发育的分子机理研究,2020.10.1-2023.9.30,参与

[5] 浙江省舟山市嵊泗县枸杞乡人民政府枸杞岛海域贻贝养殖的种质、环境及养殖策略研究课题2019.6-2021.5,参与

[6] 国家重点研发计划政府间国际科技创新合作重点专项通过比较基因组学方法解析贻贝属免疫组库,2017.04-2019.03,参与

[7] 国家自然科学基金面上项目厚壳贻贝稚贝附着机理研究,2015.01- 2018.12,参与

[8] 上海市科委重点基础项目东海海域五个主要细菌类群的附着与控制技术,2012.09-2015.06,参与

 

发表的主要论文情况(近五年)

[1] He CH, Zhang W, Hu XM, Asami Yoshida, Kiyoshi Osatomi, Liang X*, Yang JL*. 2023. Larval settlement and metamorphosis of Mytilus coruscus in response to varying bacterial capsular polysaccharide. Frontiers in Marine Science. 10:95. (IF: 5.247,5-yr IF: 5.72) Q1 

[2] Zhu YT, Liang LL, Liu TT, Liang X, Yang JL*. 2023. Effects of L-Arginine on Nitric Oxide Synthesis and Larval Metamorphosis of Mytilus coruscus. Genes, 14(2), 450. (IF: 4.141,5-yr IF: 4.474) Q2

[3] Zhang W, Wang YY, Hu XM, Zhou ZS, Zhu, YT, Liang X, Yang JL*. 2022. AMPK Promotes Larval Metamorphosis of Mytilus coruscus. Genes. 13 (12), 2384. (IF: 4.141,5-yr IF: 4.474) Q2

[4] Wang M, Xia J, Jawad M, Wei WB, Gui L, Liang X, Yang JL, Li MY*. 2022. Transcriptome sequencing analysis of sex-related genes and miRNAs in the gonads of Mytilus coruscus. Frontiers in Marine Science. 9:1013857. (IF: 5.247,5-yr IF: 5.72) Q1

[5] Li JZ, Zhang C, Hu XM, Asami Y, Kiyoshi O,Guo XP, Yang JL, Liang X. 2022. Impact of diferent enzymes on bioflm formation and mussel settlement. Scientific Reports. 2022, 12: 4685. (IF: 4.997,5-yr IF: 5.516) Q2

[6] Tan JY, Liang X, Yanv JL, Zhou SX*. 2022. Sol–gel-derived hard coatings from tetraethoxysilane and organoalkoxysilanes bearing zwitterionic and isothiazolinone groups and their antifouling behaviors. Journal of Materials Chemistry B. 10(3): 406-417. (IF: 7.571, 5-yr IF: 6.788) Q1

[7] Liang X, Zhang JB, Shao AQ, Hu XM, Wan R*, Yang JL*. 2021. Bacterial cellulose synthesis gene regulates cellular c-di-GMP that control Biofilm formation and mussel larval settlement. International Biodeterioration & Biodegratation. 165:105330. (IF: 4.907, 5-yr IF: 5.354) Q2

[8] Hu XM, Zhang JB, Ding WY, Liang X, Wan R, Dobretsov S. Yang JL*. 2021. Reduction of mussel metamorphosis by inactivation of the bacterial thioesterase gene via alteration of the fatty acid composition. Biofouling. 37(8): 911-921. (IF: 3.797, 5-yr IF: 3.944) Q2

[9] Li YF*, Wang YQ, Zheng Y, Shi X, Wang C, Cheng YL, Zhu X, Yang JL, Liang X*. 2021. Larval metamorphosis is inhibited by methimazole and propylthiouracil that reveals possible hormonal action in the mussel Mytilus coruscus. Scientific Reports, 11(1):19288. (IF: 4.997, 5-yr IF: 5.516) Q2

[10] Chang RH, Feng DD, Peng LH, Zhu YT, Liang X*, Yang JL. 2021. Complete genome sequence of Shewanella marisflavi ECSMB14101, a red pigment synthesizing bacterium isolated from the East China Sea. Marine Genomic. 58, 100846. (IF: 2.143, 5-yr IF=2.218) Q4

[11] Yang JL*, Feng DD, Liu J, Xu JK, Chen K, Li YF, Zhu YT, Liang X, Lu Y*. 2021. Chromosome-level genome assembly of the hard-shelled mussel Mytilus coruscus, a widely distributed species from the temperate areas of East Asia. Giga Science, 10(4): giab024. (IF: 7.658, 5-yr IF: 8.439) Q1

[12] Chang RH, Yang LT, Luo M, Yihan Fang Y, Peng LH, Yuli Wei Y, Fang J, Yang JL*, Liang X*. 2021. Deep‑sea bacteria trigger settlement and metamorphosis of the mussel Mytilus coruscus larvae. Scientific Reports. 11(1): 919. (IF: 4.997,5-yr IF: 5.516) Q2

[13] Li YF, Yang XY, Cheng ZY, Wang LY, Wang WX, Liang X, Yang JL*. 2020. Near-future levels of ocean temperature weaken the byssus production and performance of the mussel Mytilus coruscus. Science of the Total Environment. 733:139347. (IF:10.754, 5-yr IF: 10.237) Q1

[14] Li YF, Zhu X, Cheng ZY, Liang X, Zhu YT, Feng DD, Dobretsov S, Yang JL*. 2020. 2(5H)-Furanone disrupts bacterial biofilm formation and indirectly reduces the settlement of plantigrades of the mussel Mytilus coruscus. Frontiers in Marine Science. 7:564075. (IF:5.247, 5-yr IF: 5.72) Q1

[15] Peng LH, Liang X, Chang RH, Mu JY, Chen HE, Yoshida A, Osatomi K, Yang JL*. 2020. A bacterial polysaccharide biosynthesis-related gene inversely regulates larval settlement and metamorphosis of Mytilus coruscus. Biofouling. 36(7): 753-765. (IF:3.797, 5-yr IF: 3.944) Q2

[16] Zhu YT, Zhang Y, Liu YZ, Li YF, Yoshida A, Osatomi K, Yang JL*, Liang X*. 2020. Nitric oxide negatively regulates larval metamorphosis in hard-shelled mussel (Mytilus coruscus). Frontiers in Marine Science. 7:356. (IF:5.247, 5-yr IF: 5.72) Q1

[17] Liang X, Zhang XK, Peng LH, Zhu YT, Yoshida A, Osatomi K, Yang JL*. 2020. The flagellar gene regulates biofilm formation and mussel larval settlement and metamorphosis. International Journal of Molecular Sciences. 21(3):710. (IF:6.608, 5-yr IF: 6.628) Q1

[18] Peng LH, Liang X, Xu JK, Dobretsov S, Yang JL*. 2020. Monospecific biofilms of Pseudoalteromonas promote larval settlement and metamorphosis of Mytilus coruscus. Scientific Reports. 10(1):2577. (IF: 4.997, 5-yr IF: 5.516) Q2

[19] Li YF, Cheng YL, Chen K, Cheng ZY, Zhu X, Cardoso JCR, Liang X, Zhu YT, Power DM, Yang JL*. 2020. Thyroid hormone receptor: A new player in epinephrine-induced larval metamorphosis of the hard-shelled mussel. General and Comparative Endocrinology 287:113347. (IF:3.225, 5-yr IF: 3) Q3

[20] Li YF, Chen YW, Xu JK, Ding WY, Shao AQ, Zhu YT, Wang C, Liang X*, Yang JL*. 2019. Temperature elevation and Vibrio cyclitrophicus infection reduce the diversity of haemolymph microbiome of the mussel Mytilus coruscus. Scientific Reports. 9: 16391. (IF: 4.997, 5-yr IF: 5.516) Q2

[21] Liang X, Wang JL, Liu YZ, Peng LH, Li YF, Batista FM, Power DM, Gui L*, Yang JL*, 2019. Complete genome of a marine bacterium Vibrio chagasii ECSMB14107 with the ability to infect mussels. Marine Genomics. 48: 48-51. (IF: 2.143, 5-yr IF=2.218) Q4

[22] Li YF, Xu JK, Chen YW, Ding WY, Shao AQ, Liang X, Zhu YT, Yang JL*. 2019. Characterization of gut microbiome in the mussel Mytilus galloprovincialis in response to thermal stress. Frontiers In Physiology. 10:1086. (IF: 4.755, 5-yr IF: 5.316) Q1

[23] Wang JS, Peng LH, Guo XP, Yoshida A, Osatomi K, YF Li, Yang JL*, Liang X*. 2019. Complete genome of Pseudoalteromonas atlantica ECSMB14104, a Gammaproteobacterium inducing mussel settlement. Marine Genomics. 46:54-57. (IF: 2.143, 5-yr IF=2.218) Q4

[24] Liang X, Chen K, Li YF, Bao WY, Yoshida A, Osatomi K, Yang JL*. 2019. An ɑ2-adrenergic receptor is involved in larval metamorphosis in the mussel, Mytilus coruscus. Biofouling. 35: 986-996. (IF: 3.797,5-yr IF: 3.944) Q2

[25] Li YF, Liu YZ, Chen YW, Chen K, Batista FM, Cardoso JCR, Chen YR, Peng LH, Zhang Y, Zhu YT, Liang X, Power DM, Yang JL*. 2019. Two toll-like receptors identified in the mantle of Mytilus coruscus are abundant in haemocytes. Fish & Shellfish Immunology. 90:134-140. (IF: 4.622, 5-yr IF: 4.799) Q3

[26] Liang X, Peng LH, Zhang S, Zhou SX, Yoshida A, Osatomi K, Bellou N, Guo XP*, Dobretsov S, Yang JL*. 2019. Polyurethane, epoxy resin and polydimethylsiloxane altered biofilm formation and mussel settlement. Chemosphere. 218: 599-608. (IF: 8.943, 5-yr IF: 8.52) Q1

[27] Peng LH, Liang X, Guo XP, Yoshida A, Osatomi K, Yang JL*. 2018. Complete genome of Pseudoalteromonas marina ECSMB14103, a mussel settlement-inducing bacterium isolated from the East China Sea. Marine Genomics. 41:46-49. (IF: 2.143, 5-yr IF=2.218) Q4

[28] Li YF, Yang N, Liang X, Yoshida A, Osatomi K, Power D, Batista FM, Yang JL*. 2018. Elevated seawater temperatures decrease microbial diversity in the gut of Mytilus coruscus. Frontiers In Physiology. 9:839. (IF: 4.755, 5-yr IF: 5.316) Q1

[29] Liang X, Chen YR, Gao W, Guo XP, Ding DW, Yoshida A, Osatomi K, Yang JL*. 2018. Effects on larval metamorphosis in the mussel Mytilus coruscus of compounds that at on downstream effectors of G-protein-coupled receptors. Journal of The Marine Biological Association of the United Kingdom. 98(2), 333–339. (IF:1.559, 5-yr IF: 1.697) Q3

[30] 牟嘉仪,胡晓梦,彭莉华,竹攸汀,梁箫,杨金龙. 细菌运动性对生物被膜的动态演替及其对厚壳贻贝附着的影响. 渔业科学进展, 2022

[31] 邵安琪,李嘉政,张俊波,万荣,杨金龙,梁箫. 纤维素对Pseudoalteromonas marina生物被膜生物学特性及厚壳贻贝幼虫附着变态的影响. 水产学报, 2022

[32] 张驰,王劲松,杨金龙,张俊波,万荣,梁箫*. 海假交替单胞菌(Pseudoalteromonas marina)pilZ基因缺失抑制厚壳贻贝附着变态. 海洋学报, 2022, 44(4): 95–103.

[33] 刘志显,李嘉政,梁邻利,冯丹丹,梁箫,杨金龙,竹攸汀*. 厚壳贻贝(Mytilus coruscus)McCaspase 3-4基因的克隆及其在幼虫变态中的作用. 水生生物学报, 2022, 46(08): 1168-1176.

[34] 陈慧娥,贺康,贺楚晗,竹攸汀,杨金龙,梁箫*. 藻酸盐对海假交替单胞菌生物被膜形成及厚壳贻贝附着变态的影响. 大连海洋大学学报, 2022, 37(04): 620-626.

[35] 王林雨,史雪,杨跃明,王雨晴,梁箫,杨金龙,李一峰*. GABA受体拮抗剂荷包牡丹碱和CGP52432对厚壳贻贝幼虫附着变态的影响. 水产学报, 2022, 46(06) 942-949.

[36] 蔡雨珊,任泓妤,竹攸汀,杨金龙,张俊波,万荣,梁箫*. 海假交替单胞菌fliC-02330基因缺失影响生物被膜形成及厚壳贻贝幼虫附着变态. 微生物学通报, 2021, 49(03): 899-910.

[37] 吴静娴,李嘉政,胡晓梦,丁文扬,杨金龙,梁箫* 脂多糖对细菌生物被膜形成及厚壳贻贝幼虫变态的影响. 水产学报, 2021, 46(11): 2134-2142.

[38] 徐嘉康, 王劲松,方怡涵,杨金龙,梁箫*. 厚壳贻贝肠道细菌的生物被膜对其幼虫和稚贝附着的影响. 海洋学报, 2021, 43(9): 81–91.

[39] 蔡雨珊,张秀坤,竹攸汀,杨金龙,梁箫*. 海假交替单胞菌(Pseudoalteromonas marina)鞭毛蛋白对生物被膜形成及厚壳贻贝附着的影响. 海洋学报, 2021, 43(4): 75–83.

[40] 梁箫,丁文扬,张弛,蔡雨珊,杨金龙* 3 种脂肪酸对生物被膜形成及厚壳贻贝幼虫附着变态的影响. 大连海洋大学学报, 2021, 36(4): 580-586.

[41] 杨金龙, 段志鸿, 丁文扬, 徐嘉康, 顾忠旗, 梁箫*. 维生素B7 B12 对细菌生物被膜形成及厚壳贻贝幼虫变态的影响. 渔业科学进展, 2021, 42(5): 113–123.

[42] 常睿珩,许康豪,蔡雨珊,杨金龙,梁箫*. 钙离子对海假交替单胞菌生物被膜形成及厚壳贻贝附着的影响.大连海洋大学学报, 2020,35(6): 893-900.

[43] 梁箫, 杨丽婷, 彭莉华, 魏玉利, 方家松, 杨金龙*. 不同温度下形成的深海菌膜对厚壳贻贝幼虫变态的影响. 水产学报, 2020, 44(10): 17281741.

[44] 梁箫, 童欢, 彭莉华, 杨丽婷, 常睿珩, 杨金龙*. 纤维素对海洋细菌生物被膜形成及厚壳贻贝幼虫附着变态的调控. 大连海洋大学学报, 2020, 1: 75-82.

[45] 梁箫, 刘红雨, 杨丽婷, 常睿珩, 彭莉华, 李一峰, 杨金龙*. 弧菌生物被膜的动态演替对厚壳贻贝附着的影响. 水产学报, 2020, 44(1): 118129.

[46] 梁箫, 刘钰珠, 陈珂, 李一峰, 杨金龙*. 厚壳贻贝MyD88-4基因的生物学特性及其对沙氏弧菌的免疫应答. 水产学报, 2019, 43(11):1910-1921.

[47] 梁箫,陈珂,陈艳文,刘钰珠,李一峰,杨金龙*. 厚壳贻贝5-羟色胺2A受体(5-HT2AR)基因克隆和时空表达. 水产学报, 2018, 4212):1845-1855.

[48] 梁箫,张亚,刘钰珠,李一峰,Batista M. FredericoPower Deborah,杨金龙*. 灿烂弧菌对厚壳贻贝免疫指标和消化酶活性的影响. 水产学报, 2018, 429):1438-1445.

 

申请和授权专利情况

[1] 梁箫,彭莉华,张秀坤,魏玉利,方家松,杨金龙. 一种深海盐单胞菌及其在诱导厚壳贻贝稚贝附着中的应用.授权国家发明专利号ZL201810315970.9

[2] 杨金龙,郭行磐,陈芋如,梁箫. 一株海洋希瓦氏细菌及其在诱导厚壳贻贝稚贝附着方面的应用. (授权国家发明专利号:ZL201410741373.4

[3] 杨金龙,李一峰,郭行磐,梁箫,李家乐. 碱性蛋白酶与聚二甲基硅氧烷的复合物及其制备方法和应用.(授权国家发明专利号:ZL201710318066.9

[4] 杨金龙梁箫,彭莉华,陈珂,魏玉利,方家松. 一种深海芽孢杆菌及其在诱导厚壳贻贝稚贝附着中的应用.(授权国家发明专利号ZL201810423184.0

[5] 杨金龙,彭莉华,杨丽婷,魏玉利,方家松,梁箫. 一种海洋除烃海杆细菌及其在诱导厚壳贻贝稚贝附着中的应用.授权国家发明专利号ZL201810316697.1

科教工作获奖情况

[1] 2022年上海海洋科学技术奖一等奖(排名第五)

[2] 2020年度海洋科学技术奖二等奖(排名第四)

[3] 2020年度浙江省科学技术进步奖三等奖(排名第四)

[4] 2020年度宁波市科学技术进步奖三等奖(排名第四)

[5] 2019年度上海市科技进步二等奖(排名第九)

[6] 2018年度上海市浦东新区科技进步一等奖(排名第九)

 

联系方式

地址:上海市浦东新区沪城环路999

E-mailx-liang@shou.edu.cn