基本情况：

王俊亚，博士，水产生理与医学系副教授。

1986年7月生，籍贯河南商丘，中共党员；2018年10月-2020年12月于新葡萄8883官网AMG水产养殖学博士后流动站进行博士后研究。2021年入职新葡萄8883官网AMG。主要承担本科生《微生物学》课程教学工作，讲授本科生《免疫学》，研究生《全英分子免疫学》和《水产动物医学前沿》等课程教学工作。近5年在Journal of Immunology, Fish shellfish Immunology, Developmental and Comparative Immunology, Frontiers in Immunology等期刊发表论文30余篇，其中以第一作者或通讯作者发表论文12篇。

教育背景

2013.09–2018.06，中国农业大学，农学博士学位

2010.09–2013.06，河南农业大学，农学硕士学位

2006.09–2010.06，河南农业大学，工学学士学位

招生专业：

水产养殖（学术型）/渔业发展（专业型）。

主要研究方向

1. 鱼类免疫分子和病原致病因子结构与功能的研究；

2. 鱼类免疫防御的分子机理研究；

3. 渔用疫苗研制与应用；

主持和参与的科教项目

[1] 国家自然科学基金面上项目，32373166，草鱼Meteorin-like因子调控宿主抗GCRV-II感染的功能与作用机理研究，，2024/1-2027/12，主持。

[2] 科技部外国专家项目，G2023013034L，水产免疫防控与抗病育种，2023/1-2024/12，主持。

[3] 农业农村部科技创新2030-重大项目“抗病抗逆鱼新品种设计与培育”课题1“抗出血病性状遗传多样性评估与新种质鉴定”-子课题，2023ZD0406501， 2023/9-2025/12。

[4] 广西水产生物技术与现代生态养殖重点实验室开放课题，GXABMEC2023001，3型鲤疱疹病毒IL-10功能，结构及作用机制研究，2023/6-2025/5，主持。

[5] 自然科学基金重点项目，32030112，草鱼CD4 T辅助（Th）细胞免疫系统及其应答病毒感染的分子机理研究，2021/01-2025/12，参与，排名第三。

第一或通讯作者发表论文：

[1] Zhao Jia, Jianhua Feng, Helen Dooley, Jun Zou, Junya. Wang*, The first crystal structure of CD8αα from a cartilaginous fish, Front Immunol 14 (2023), 1156219.

[2] Jiahong Guo, Wenji Huang, Xin Zhao, Ning Ji, Kangyong Chen, Yanjie Shi, Jianhua Feng, Jun Zou, Junya Wang* The expanded ISG12 family in zebrafish: ISG12.1 suppresses virus replication via targeting viral phosphoprotein. Dev Comp Immunol 142 (2023), 104672.

[3] Zhao Jia, Jianhua Feng, Gaoliang Yuan, Hehe Xiao, Huifeng Dang,Yanwei Zhang, Kangyong Chen, Jun Zou, Junya Wang*. The Meteorin-like cytokine is upregulated in grass carp after infection with Aeromonas hydrophila Dev Comp Immunol 141 (2023), 104632.

[4] Yanjie Shi, Kangyong Chen, Xin Zhao, Yanan Lu, Wenji Huang, Jiahong Guo, Ning Ji, Zhao Jia, Hehe Xiao, Huifeng Dang, Jun Zou*, Junya Wang*. IL-27 suppresses spring viremia of carp virus replication in zebrafish. Fish shellfish Immunol 133 (2023), 108530.

[5] Huifeng Dang, Zeinab Hassan, Zhao Jia, Yaxin Wu, Hehe Xiao, Wenji Huang, Xu Guo, Xin Zhao, Yaoguo Li, Jun Zou, Junya Wang* Grass carp IL-20 binds to IL-20R2 but induces STAT3 phosphorylation via IL-20R1. Fish shellfish Immunol 132 (2023), 108445.

[6] Xiaozhen Zhu^#, Junya Wang^#, Zhao Jia, Jianhua Feng, Bangjie Wang, Zixuan Wang, Qin Liu, Kaizheng Wu, Wenji Huang, Xin Zhao, Huifeng Dang, and Jun Zou*. Novel Dimeric Architecture of an IFN-gamma-Related Cytokine Provides Insights into Subfunctionalization of Type II IFNs in Teleost Fish, J Immunol. 209 (2022):2203-2214. 

[7] Zixuan Wang, Jiawen Xu, Jianhua Feng, Kaizheng Wu, Kangyong Chen, Zhao Jia, Xiaozhen Zhu, Wenji Huang, Xin Zhao, Qin Liu, Bangjie Wang, Xinhua Chen, Junya Wang*, Jun Zou*. Structural and Functional Analyses of Type I IFNa Shed Light Into Its Interaction With Multiple Receptors in Fish. Front Immunol 13 (2022): 862764.

[8] Junya Wang, Zhao Jia, Huifeng Dang, Jun Zou*. Meteorin-like/Meteorin-β upregulates proinflammatory cytokines via NF-κB pathway in grass carp Ctenopharyngodon idella. Dev Come Immunol, 127 (2022): 104289.

[9] Yaxin Wu , Zhao Jia, Huifeng Dang , Hehe Xiao , Wenji Huang , Qin Liu, Kangyong Chen, Lei Zhang, Jun Zou and Junya Wang*. Molecular Characterization, Evolution and Expression Analysis of TNFSF14 and Three TNFSF Receptors in Spotted Gar Lepisosteus oculatus. Journal of Marine Science and Engineering 10 (2022), 1035.

[10] Junya Wang, Wei Wang, Jiawen Xu, Zhao Jia, Qin Liu, Xiaozhen Zhu, Chun Xia*, Jun Zou*. Structural insights into the co-evolution of IL-2 and its private receptor in fish. Dev Comp Immunol 115 (2020), 103895.

[11] Xinyu Jiang^#, Junya Wang^#, Shuai Wan, Yujie Xue, Zhaosheng Sun, Xingxing Cheng, Qian Gao*, Jun Zou*. Distinct expression profiles and overlapping functions of IL-4/13A and IL-4/13B in grass carp (Ctenopharyngodon idella), Aquaculture and Fisheries 5 (2020), 72-79.

[12] Junya Wang, Nianzhi Zhang, Zhenbao Wang, Yanan wu, Lijie Zhang, Chun Xia*. Structural insights into the evolution feature of a bony fish CD8alphaalpha homodimer. Mol Immunol 97 (2018) 109-116.

其它发表论文：

[1] Wenji Huang, Xin Zhao, Ning Ji, Jiahong Guo, Jianhua Feng, Kangyong Chen, Yaxin Wu, Junya Wang, Hao Feng, Jun Zou*. IRF2 cooperates with phosphoprotein of spring viremia of carp virus to suppress antiviral response in zebrafish, J Virol. 96 (2022) e0131422.

[2] Bangjie Wang, Yuting Qin, Zhaosheng Sun, Xiaozhen Zhu, Zhao Jia, Kangyong Chen, D. Liu, Junya Wang, Jun Zou*. Production and characterization of monoclonal antibodies against grass carp CD4-1 and CD4-2, Aquaculture and Fisheries (2022).

[3] Yaxin Wu, Yibin Yang, Huifeng Dang, Hehe Xiao, Wenji Huang, Zhao Jia, Xin Zhao, Kangyon Chen, Ning Ji, Jiahong Guo, Zhiwei Qin, Junya Wang, Jun Zou*. Molecular identification of Klebsiella pneumoniae and expression of immune genes in infected spotted gar Lepisosteus oculatus, Fish Shellfish Immunol 119 (2021) 220-230.

[4] Zhaosheng Sun, Yuting Qin, Danjie Liu, Bangjie Wang, Zhao Jia, Junya Wang, Qian Gao*, Jun Zou*, Yue Pang*. The evolution and functional characterization of CXC chemokines and receptors in lamprey, Dev Comp Immunol 116 (2021) 103905.

[5] Kangyong Chen, Jiayin Tian, Junya Wang, Zhao Jia, Qin Zhang, Wenji Huang, Xin Zhao, Zhipeng Gao, Qian Gao, Jun Zou*. Lipopolysaccharide-induced TNFα factor (LITAF) promotes inflammatory responses and activates apoptosis in zebrafish Danio rerio, Gene 780 (2021) 145487.

[6] Yuting Qin, Zhaosheng Sun, Wei Wang, Jiawen Xu, Bangjie Wang, Zhao Jia, Xia Li, Junya Wang, Qian Gao, Xinhua Chen, Jun Zou*. Characterization of CD3γ/δ+ cells in grass carp (Ctenopharyngodon idella), Dev Comp Immunol 114 (2021) 103791.

[7] Wei Wei, Junya Wang, Qingyu Min, Zhao Jia, Kangyuong Chen, Hao Feng, Jun Zou*. CCL19 variants mediate chemotactic response via CCR7 in grass carp Ctenopharyngodon idella, Dev Comp Immunol 122 (2021) 104127.

[8] Zhao Jia, Junya Wang, Kangyong Chen, Qin Zhang, Zhaosheng Sun, Zeinab Hassan, Hao Feng, Jun Zou*. Identification and expression analysis of group II C-type lectin domain containing receptors in grass carp Ctenopharyngodon idella, Gene 789 (2021) 145668.

[9] Zeinab Hassan, Junya Wang, Yuting Qin, Wei Wang, Qin Liu, Lina Lei, Zhaosheng Sun, Yibin Yang, Kaizheng Wu, Xiaozhen Zhu, Zixuan Wang, Hao Feng, Jun Zou*. Functional characterization of an interleukin 20 like homologue in grass carp Ctenopharyngodon idella, Fish Shellfish Immunol 115 (2021) 43-57.

[10] Wei Wang, Junya Wang, Lina Lei, Jiawen Xu, Yuting Qin, Qian Gao*, Jun Zou* Characterisation of IL-15 and IL-2Rβ in grass carp: IL-15 upregulates cytokines and transcription factors of type 1 immune response and NK cell activation, Fish Shellfish Immunol 107 (Pt A) (2020) 104-117.

[11] Yibin Yang, Junya Wang, Jiawen Xu, Qin Liu, Zixuan Wang, Xiaozhen Zhu, Xiaohui Ai, Qian Gao, Xinhua Chen, Jun Zou*. Characterization of IL-22 bioactivity and IL-22-positive cells in grass carp Ctenopharyngodon idella, Front Immunol 11 (2020) 586889.

[12] Chang Zhang, Qin Zhang, Junya Wang, Jiayin Tian, Yunjie Song, Haixia Xie, Mingxian Chang, Pin Nie, Qian Gao*, Jun Zou*. Transcriptomic responses of S100 family to bacterial and viral infection in zebrafish, Fish Shellfish Immunol 94 (2019) 685-696.

[13] Yujie Xue, Xinyu Jiang, Jingduo Gao, Xia Li, Jiawen Xu, Junya Wang, Qian Gao* Jun Zou*. Functional characterization of interleukin 34 in grass carp Ctenopharyngodon idella, Fish Shellfish Immunol 92 (2019) 91-100.

[14] 季宁，魏伟，郭家鸿，王俊亚，李耀国，肖调义，邹钧. 草鱼呼肠孤病毒VP7蛋白单克隆抗体的制备与应用[J]. 水生生物学报，2022，46(9)：1293−1300

[15] 刘琴，贾钊，陈康勇，朱晓真，王梓璇，陈静，王俊亚，李耀国，肖调义，邹钧，草鱼IL-10单克隆抗体的制备与鉴定[J].水生生物学报，2022，46(12)：1867-1875.

[16] 王梓璇，贾钊，邬恺正，朱晓真，王俊亚，冯浩，邹钧，草鱼IFNa和IFNd重组蛋白表达、纯化及单克隆抗体制备[J]. 水产学报，2022，46(11)：1−13

[17] 朱晓真，王俊亚，贾钊，王梓璇，王邦杰，邹钧，草鱼Ⅱ型干扰素的单克隆抗体制备与鉴定[J].水产学报，2022，46(8)：1487−1498

[18] 邹钧，邬恺正，王俊亚，范丁月，李仕然，徐兢，王梓璇，草鱼芳香烃受体ahr1a基因克隆、表达及进化分析[J].新葡萄8883官网AMG学报，2023，32(1)：40-52.

申请和授权专利情况

[1] 王俊亚，肖贺贺，邹钧，运胜冉，分泌抗草鱼IL-4/13B单克隆抗体的杂交瘤细胞株及单克隆抗体和应用。发明专利号申请号：202211039180.5。

[2] 王俊亚，陈静，邹钧，桂朗，刘琴，分泌抗鲤科疱疹病毒3型IL-10单克隆抗体的杂交瘤细胞株、单克隆抗体和应用。发明专利号申请号：202211038900.6。

联系方式

地址：新葡萄8883官网AMGE楼103室

E-mail：jywang@shou.edu.cn